Call 8872524007 to book a collection time.
What the HLA-B27 test checks
This is a genetic marker test, not an antibody test. Most labs use flow cytometry, which looks for the HLA-B27 antigen on white cells; some use PCR to detect the gene. The answer is simply positive or negative. Since your genes don't change, the test only needs to be done once in a lifetime.
Why your doctor may order it
HLA-B27 is linked with a group of conditions called spondyloarthritis. Doctors usually order the test when someone has:
- low back pain and stiffness for three months or more that starts before 45, is worse in the morning or after rest, and eases with movement
- pain in the buttocks or sacroiliac joints, sometimes switching sides
- swelling of a few large joints, heel pain or a "sausage" finger or toe
- repeated attacks of a red, painful eye (anterior uveitis)
- joint pain after a gut or urinary infection (reactive arthritis), or with psoriasis or inflammatory bowel disease
How to prepare
No fasting and no special timing. Tell us when you book, because the sample is whole blood and has to reach processing within a fixed window; we'll give you a suitable collection day and time.
Sample type and report time
- Sample: whole blood in an EDTA tube (purple cap), not serum
- Fasting: not needed
- Report: usually 1–3 working days. We'll tell you the expected date when you book.
For a home collection that fits the transport window, book on 8872524007.
Understanding your results
A positive result means you carry HLA-B27. Most people with ankylosing spondylitis test positive (often around 80 to 90% in published studies), yet only a small fraction of all carriers ever develop it. The marker is found in a few percent of the general population in India, so a positive result in someone without typical symptoms means little on its own.
A negative result makes ankylosing spondylitis less likely but doesn't exclude it or other forms of spondyloarthritis. Doctors combine the test with your history, examination, inflammatory markers such as ESR and CRP, and imaging such as X-ray or MRI of the sacroiliac joints. Your doctor reads the result alongside your symptoms and other tests.
FAQ
Does a positive HLA-B27 mean I have ankylosing spondylitis?
No. Many people carry HLA-B27 and stay well. It raises the likelihood when symptoms fit, and your doctor makes the diagnosis using other findings too.
Do I need to repeat the HLA-B27 test?
No. It's an inherited marker, so the result stays the same for life. Keep the report safely.
Is there an HLA B27 test near me in Banur?
Yes. We collect the EDTA sample at Alpha Laboratory on M.C. Road, or at home through home sample collection by arrangement.
Should my children be tested if I'm HLA-B27 positive?
Each child usually has about a one-in-two chance of inheriting it, but testing children without symptoms is usually not helpful. Discuss it with your doctor.
Book at Alpha Laboratory
Book an HLA-B27 test in Banur on 8872524007 or WhatsApp us so we can plan a collection time that suits processing. See the contact page for hours.